CD82 抗体 (AA 98-267) (FITC)
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北京 101111
Quick Overview for CD82 抗体 (AA 98-267) (FITC) (ABIN7977466)
抗原
See all CD82 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 98-267
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原理
- Anti-CD82 Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human CD82 shares 69%,67% amino acid (aa) sequences identity with mouse,rat CD82,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD82 recombinant protein (Position: A98-Y267). Human CD82 shares 69% and 67% amino acid (aa) sequences identity with mouse and rat CD82, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CD82
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别名
- CD82
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背景
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Background: CD82 (Cluster of Differentiation 82), also named KAI1, is a protein that in humans encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.
Gene Full Name: CD82 Molecule
Sequence Similarities: Belongs to the tetraspanin (TM4SF) family.
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基因ID
- 3732
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UniProt
- P27701
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途径
- p53 Pathway
抗原
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