CD68 抗体 (Middle Region)
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Quick Overview for CD68 抗体 (Middle Region) (ABIN7977284)
抗原
See all CD68 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Middle Region
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原理
- Anti-Macrosialin CD68 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat sequence by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse CD68, different from the related rat sequence by one amino acid.
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亚型
- IgG
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anti-CD68 Molecule (CD68) (Middle Region) antibody
CD68 适用: 小鼠, 大鼠 IHC, FACS, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD68 Molecule (CD68) (AA 42-155) antibodyCD68 适用: 人 IHC, FACS, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3F7D3 unconjugated
anti-CD68 Molecule (CD68) antibodyCD68 适用: 人, 小鼠, 大鼠, 猴 IHC, FACS, WB, IF 宿主: 小鼠 Monoclonal C68-684 unconjugated
anti-CD68 Molecule (CD68) (AA 22-319) antibodyCD68 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), ICC, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD68 Molecule (CD68) antibodyCD68 适用: 人 IHC, FACS, IF (p), mIF 宿主: 小鼠 Monoclonal KP-1 unconjugated Recombinant Antibody
anti-CD68 Molecule (CD68) antibodyCD68 适用: 人 IHC, FACS, WB, IF 宿主: 小鼠 Monoclonal rLAMP4-824 unconjugated Recombinant Antibody
anti-CD68 Molecule (CD68) (AA 150-301) antibodyCD68 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal LAMP4-1830 unconjugated
anti-CD68 Molecule (CD68) (AA 154-354) antibodyCD68 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD68 Molecule (CD68) (AA 150-221) antibodyCD68 适用: 人 IHC 宿主: 小鼠 Monoclonal C68-2709 unconjugated
anti-CD68 Molecule (CD68) antibody (PE)CD68 适用: 人 FACS 宿主: 小鼠 Monoclonal Y1-82A PE
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应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunofluorescence, 5 μg/mL, Mouse Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Mouse
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CD68 (CD68 Molecule (CD68))
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别名
- CD68
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背景
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Background: CD68 is a heavily glycosylated glycoprotein that is highly expressed in macrophages and other mononuclear phagocytes. Macrosialin, if not glycosylated, has the main sequence that consists of 354 amino acids with an expected molecular weight of 37.4 kD. CD68, which can be located in the cytoplasmic granules of a variety of blood cells and myocytes, can be detected via immunohistochemistry. It's particularly effective as a marker for monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts, all of which belong to the macrophage lineage. CD68 is expressed in tissue macrophages and to a lesser extent in dendritic cells. CD68 is involved in tissue macrophage phagocytic activities, as well as intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It works by binding to tissue and organ-specific lectins or selectins, enabling macrophage subsets to be ed to specific locations. Macrophages may be able to crawl over selectin-bearing substrates or other cells if CD68 is rapidly recirculated from endosomes and lysosomes to the plasma membrane.
Gene Full Name: CD68 antigen
Sequence Similarities: Belongs to the LAMP family.
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分子量
- 90-100 kDa
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基因ID
- 12514
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UniProt
- P31996
抗原
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