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CD59 抗体 (AA 26-102) (Fluoro594)

This 兔 多克隆 antibody specifically detects CD59 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7977168
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for CD59 抗体 (AA 26-102) (Fluoro594) (ABIN7977168)

抗原

See all CD59 抗体
CD59

适用

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宿主

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克隆类型

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多克隆

标记

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This CD59 antibody is conjugated to Fluoro594

应用范围

  • 144
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Flow Cytometry (FACS)
  • 抗原表位

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    AA 26-102

    原理

    Anti-CD59 glycoprotein CD59 Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CD59 shares 47.1% amino acid (aa) sequence identity with rat CD59.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD59 recombinant protein (Position: L26-N102). Human CD59 shares 47.1% amino acid (aa) sequence identity with rat CD59.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CD59

    别名

    CD59

    背景

    Background: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. And this protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

    Gene Full Name: CD59 Molecule (CD59 blood group)

    Sequence Similarities: Contains 1 UPAR/Ly6 domain.

    基因ID

    966

    UniProt

    P13987

    途径

    Complement System
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