CD46 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CD46 抗体 (N-Term) (ABIN7977031)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- N-Term
-
原理
- Anti-CD46 Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
预测反应
- different from the related human sequence by twelve amino acids,and from the related rat sequence by nine amino acids.
-
产品特性
- Anti-CD46 Antibody. Tested in WB applications. This antibody reacts with Mouse.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD46, different from the related human sequence by twelve amino acids, and from the related rat sequence by nine amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- CD46
-
别名
- Cd46
-
背景
-
Background: CD46 complement regulatory protein,?also known as?CD46 (cluster of differentiation?46) and?Membrane Cofactor Protein,?is a?protein?which in humans is encoded by the?CD46 gene. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.?
Gene Full Name: CD46 antigen, complement regulatory protein
-
分子量
- 41 kDa, 70 kDa
-
基因ID
- 17221
-
UniProt
- O88174
-
途径
- Regulation of Actin Filament Polymerization
抗原
-