CD226 抗体 (AA 31-333) (Fluoro647)
Our Local Distributor
北京 101111
Quick Overview for CD226 抗体 (AA 31-333) (Fluoro647) (ABIN7976546)
抗原
See all CD226 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 31-333
-
原理
- Anti-CD226 Antibody Fluoro647 Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived mouse CD226 recombinant protein (Position: E31-L333).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- CD226
-
别名
- Cd226
-
背景
-
Background: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
Gene Full Name: CD226 antigen
-
基因ID
- 225825
-
UniProt
- Q8K4F0
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
-