DC-SIGN/CD209 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for DC-SIGN/CD209 抗体 (N-Term) (ABIN7976503)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- N-Term
-
原理
- Anti-DC-SIGN/CD209 Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-DC-SIGN/CD209 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human DC-SIGN.
-
亚型
- IgG
-
-
anti-CD209 (CD209) (AA 70-404) antibody
CD209 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C209-1781 unconjugated
anti-CD209 (CD209) (AA 270-404) antibodyCD209 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
anti-CD209 (CD209) (AA 1-404) antibodyCD209 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 IHC, FACS, IHC (p), IP 宿主: 大鼠 Monoclonal h209 unconjugated
anti-CD209 (CD209) (AA 297-380) antibodyCD209 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD209 (CD209) (AA 271-380) antibodyCD209 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal rC209-1781 unconjugated Recombinant Antibody
anti-CD209 (CD209) (AA 265-404) antibodyCD209 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- DC-SIGN/CD209 (CD209) (CD209)
-
别名
- CD209
-
背景
-
Background: DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209 (Cluster of Differentiation 209) is a protein which in humans is encoded by the CD209 gene. This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene. DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.
Gene Full Name: CD209 Molecule
-
分子量
- 46 kDa
-
基因ID
- 30835
-
UniProt
- Q9NNX6
抗原
-
