CD2AP 抗体 (AA 253-337) (HRP)
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Quick Overview for CD2AP 抗体 (AA 253-337) (HRP) (ABIN7976477)
抗原
See all CD2AP (Cd2ap) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 253-337
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原理
- Anti-CD2AP Antibody (monoclonal, 5F8) HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
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亚型
- IgG1
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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别名
- CD2AP
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背景
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Background: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein ly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Gene Full Name: CD2 associated protein
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基因ID
- 23607
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UniProt
- Q9Y5K6
抗原
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