CD2AP 抗体 (AA 320-400)
Our Local Distributor
北京 101111
Quick Overview for CD2AP 抗体 (AA 320-400) (ABIN7227732)
抗原
See all CD2AP (Cd2ap) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 320-400
-
原理
- Rabbit Anti-CD2AP Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of CD2AP protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human CD2AP protein at AA range: 320-400
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
-
别名
- CD2AP
-
背景
- CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domainsCD2AP (CD2 Associated Protein) encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of CD2AP is implicated in susceptibility to glomerular disease. CD2AP is a Protein Coding gene. Diseases associated with CD2AP include Glomerulosclerosis, Focal Segmental, 3 and Sporadic Idiopathic Steroid-Resistant Nephrotic Syndrome With Focal Segmental Hyalinosis.
-
分子量
- 70kD
-
基因ID
- 23607
-
UniProt
- Q9Y5K6
抗原
-