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CD2AP 抗体 (AA 253-337) (Cy3)

This 小鼠 单克隆 antibody specifically detects CD2AP in FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7976472
发货至: 中国
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Quick Overview for CD2AP 抗体 (AA 253-337) (Cy3) (ABIN7976472)

抗原

See all CD2AP (Cd2ap) 抗体
CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

适用

人, 大鼠, 小鼠

宿主

  • 35
  • 11
小鼠

克隆类型

  • 35
  • 11
单克隆

标记

  • 18
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD2AP antibody is conjugated to Cy3

应用范围

  • 20
  • 19
  • 16
  • 14
  • 9
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

5F8
  • 抗原表位

    • 23
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 253-337

    原理

    Anti-CD2AP Antibody (monoclonal, 5F8) Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human CD2AP recombinant protein (Position: K253-K337).

    亚型

    IgG1
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

    别名

    CD2AP

    背景

    Background: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein ly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

    Gene Full Name: CD2 associated protein

    基因ID

    23607

    UniProt

    Q9Y5K6
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