Cathepsin B 抗体 (AA 42-339) (Biotin)
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北京 101111
Quick Overview for Cathepsin B 抗体 (AA 42-339) (Biotin) (ABIN7975800)
抗原
See all Cathepsin B (CTSB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-339
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原理
- Anti-Cathepsin B/CTSB Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cathepsin B/CTSB recombinant protein (Position: Q42-K339).
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亚型
- IgG
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anti-Cathepsin B (CTSB) (AA 1-339) antibody
CTSB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 251-339) antibodyCTSB 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 82-333) antibodyCTSB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 42-339) antibodyCTSB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 1-339) antibodyCTSB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin B (CTSB) antibodyKD Validated CTSB 适用: 人 WB 宿主: 兔 Monoclonal 23GB1130 unconjugated Recombinant Antibody
anti-Cathepsin B (CTSB) antibodyCTSB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Cathepsin B (CTSB)
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别名
- CTSB
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背景
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Background: Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene. And this gene is mapped to chromosome 8p22. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of beta-amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade beta-amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. The standard product used in this kit is recombinant human Cathepsin B with the molecular mass of 37KDa.
Gene Full Name: cathepsin B
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基因ID
- 1508
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UniProt
- P07858
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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