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Cathepsin B 抗体

CTSB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266148
发货至: 中国
  • 抗原 See all Cathepsin B (CTSB) 抗体
    Cathepsin B (CTSB)
    适用
    • 58
    • 27
    • 24
    • 7
    • 1
    • 1
    宿主
    • 45
    • 12
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 48
    • 16
    单克隆
    标记
    • 30
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin B antibody is un-conjugated
    应用范围
    • 46
    • 24
    • 20
    • 17
    • 14
    • 13
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Cathepsin B Rabbit mAb
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Cathepsin B
    亚型
    IgG
    Top Product
    Discover our top product CTSB Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Cathepsin B (CTSB)
    别名
    CTSB (CTSB 产品)
    别名
    APPS antibody, CPSB antibody, CB antibody, apps antibody, cpsb antibody, LOC692390 antibody, CTSB antibody, cathepsin B antibody, cathepsin B S homeolog antibody, CTSB antibody, Ctsb antibody, ctsb.S antibody, LOC692390 antibody
    背景
    This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Nov 2015],APPS;CPSB;Cathepsin B;CTSB,Apoptosis,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Invasion and Metastasis,Neuroscience,Signal Transduction,CTSB
    分子量
    38kDa
    基因ID
    1508
    UniProt
    P07858
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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