CASP5 抗体 (AA 137-434) (PE)
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Quick Overview for CASP5 抗体 (AA 137-434) (PE) (ABIN7975368)
抗原
See all CASP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 137-434
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原理
- Anti-Caspase-5/CASP5 Antibody PE Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Caspase-5/CASP5 recombinant protein (Position: D137-N434).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
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别名
- CASP5
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背景
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Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
Gene Full Name: caspase 5
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基因ID
- 838
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UniProt
- P51878
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途径
- Inflammasome
抗原
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