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CASP5 抗体 (AA 162-191)

This 兔 多克隆 antibody specifically detects CASP5 in WB, FACS 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN654898
发货至: 中国
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Quick Overview for CASP5 抗体 (AA 162-191) (ABIN654898)

抗原

See all CASP5 抗体
CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

适用

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宿主

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克隆类型

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多克隆

标记

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This CASP5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB18988
  • 抗原表位

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    AA 162-191

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CASP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

    别名

    CASP5

    背景

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

    分子量

    49736

    基因ID

    838

    NCBI登录号

    NP_001129581, NP_001129582, NP_001129584, NP_004338

    UniProt

    P51878

    途径

    Inflammasome
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