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CASP5 抗体 (AA 137-434) (APC)

The APC-conjugated 兔 多克隆 anti-CASP5 antibody (ABIN7975367) specifically detects CASP5 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7975367
发货至: 中国
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Quick Overview for CASP5 抗体 (AA 137-434) (APC) (ABIN7975367)

抗原

See all CASP5 抗体
CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

适用

  • 67
  • 20
  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 64
  • 3

克隆类型

  • 46
  • 21
多克隆

标记

  • 32
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CASP5 antibody is conjugated to APC

应用范围

  • 42
  • 20
  • 18
  • 17
  • 15
  • 15
  • 12
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 137-434

    原理

    Anti-Caspase-5/CASP5 Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Caspase-5/CASP5 recombinant protein (Position: D137-N434).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

    别名

    CASP5

    背景

    Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

    Gene Full Name: caspase 5

    基因ID

    838

    UniProt

    P51878

    途径

    Inflammasome
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