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Caspase 2 抗体 (C-Term) (Fluoro647)

The Fluoro647-conjugated 兔 多克隆 anti-Caspase 2 antibody (ABIN7975226) specifically detects Caspase 2 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7975226
发货至: 中国
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Quick Overview for Caspase 2 抗体 (C-Term) (Fluoro647) (ABIN7975226)

抗原

See all Caspase 2 (CASP2) 抗体
Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

适用

  • 151
  • 90
  • 74
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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人, 小鼠, 大鼠

宿主

  • 149
  • 4
  • 3

克隆类型

  • 126
  • 30
多克隆

标记

  • 71
  • 11
  • 8
  • 5
  • 4
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Caspase 2 antibody is conjugated to Fluoro647

应用范围

  • 97
  • 48
  • 42
  • 35
  • 24
  • 22
  • 14
  • 14
  • 11
  • 10
  • 4
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 27
    • 16
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Caspase-2/CASP2 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse,rat sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Caspase-2, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

    别名

    CASP2

    背景

    Background: CASP2 is equal to Caspase-2. And Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. It is showed that activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.

    Gene Full Name: caspase 2

    Sequence Similarities: Belongs to the peptidase C14A family.

    基因ID

    835

    UniProt

    P42575

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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