Calpain 6 抗体 (AA 1-641) (Fluoro647)
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Quick Overview for Calpain 6 抗体 (AA 1-641) (Fluoro647) (ABIN7974389)
抗原
See all Calpain 6 (CAPN6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-641
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原理
- Anti-Calpain 6/CAPN6 Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human Calpain 6,CAPN6 shares 95.2%,95% amino acid (aa) sequence identity with mouse,rat Calpain 6,CAPN6,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Calpain 6/CAPN6 recombinant protein (Position: M1-L641). Human Calpain 6/CAPN6 shares 95.2% and 95% amino acid (aa) sequence identity with mouse and rat Calpain 6/CAPN6, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Calpain 6 (CAPN6)
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别名
- CAPN6
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背景
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Background: Calpain-6 (also known as calpamodulin) is a protein in humans that is encoded by the CAPN6 gene. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
Gene Full Name: calpain 6
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基因ID
- 827
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UniProt
- Q9Y6Q1
抗原
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