CAPNL1 抗体 (Middle Region) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for CAPNL1 抗体 (Middle Region) (Cy3) (ABIN7974326)
抗原
See all CAPNL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- Anti-Calpain 1/CAPN1 Antibody Cy3 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- different from the mouse sequence by two amino acids.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Calpain 1, different from the mouse sequence by two amino acids.
-
亚型
- IgG
-
-
anti-Calpain 1, Large Subunit (CAPNL1) antibody
CAPNL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 501-714) antibodyCAPNL1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B2G10 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 20-330) antibodyCAPNL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 501-714) antibodyCAPNL1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1E6G9 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (Middle Region) antibodyCAPNL1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 1-420) antibodyCAPNL1 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1376CT809-24-85 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 75-343) antibodyCAPNL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 1-714) antibodyCAPNL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
-
别名
- CAPN1
-
背景
-
Background: Calpain-1 catalytic subunit is a protein that in humans is encoded by the CAPN1 gene. Calpain is an intracellular protease that requires calcium for its catalytic activity. Two isozymes, calpain I (mu-calpain) and calpain II (m-calpain), with different calcium requirements, have been identified. Both are heterodimers composed of L (large, catalytic, 80 kD) and S (small, regulatory, 30 kD) subunits. The isozymes share an identical S subunit, with the differences arising from the L subunits, L1 (CAPN1) and L2. By quantitative RT-PCR, Ueyama et al. (1998) found that expression of calpain-1 and calpain-2 mRNA was significantly increased in muscle biopsy samples derived from 5 men with progressive muscular dystrophy (e.g., DMD, 310200) and 2 men and 3 women with amyotrophic lateral sclerosis (ALS, 105400) compared with controls. Using cDNA clones as probes, Ohno et al. (1989, 1990) assign CANPL1 to chromosome 11.
Gene Full Name: calpain 1
Sequence Similarities: Belongs to the peptidase C2 family.
-
基因ID
- 823
-
UniProt
- P07384
-
途径
- Apoptosis
抗原
-
