CTBP1 抗体 (C-Term) (HRP)
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北京 101111
Quick Overview for CTBP1 抗体 (C-Term) (HRP) (ABIN7973692)
抗原
See all CTBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-C-terminal-binding protein 1 CtBP1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat,mouse sequences by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CtBP1, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-C-terminal Binding Protein 1 (CTBP1) (AA 1-429) antibody
CTBP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (AA 20-250) antibodyCTBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) antibodyKD Validated CTBP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2330 unconjugated Recombinant Antibody
anti-C-terminal Binding Protein 1 (CTBP1) (pSer422) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibodyCTBP1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (AA 413-440) antibodyCTBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (C-Term) antibodyCTBP1 适用: 人, 小鼠, 大鼠, Pig, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 1 (CTBP1) (pSer422) antibodyCTBP1 适用: 大鼠, 斑马鱼 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CTBP1 (C-terminal Binding Protein 1 (CTBP1))
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别名
- CTBP1
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背景
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Background: CTBP1, C-terminal-binding protein 1, is a protein that in humans is encoded by the CTBP1 gene. The CtBP1 protein binds to the C-terminus of adenovirus E1A proteins. This gene is mapped to 4p16. This phosphoprotein is a transcriptional repressor (corepressor) and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. CtBP1 and CtBP2 preferentially associate with the E1A via a 5 amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of delta EF1, a cellular zinc finger-homeodomain protein, and thereby enhances delta EF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a 125 kDa protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Gene Full Name: C-terminal binding protein 1
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基因ID
- 1487
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UniProt
- Q13363
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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