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BCAR3 抗体 (C-Term) (FITC)

The FITC-conjugated 兔 多克隆 anti-BCAR3 antibody (ABIN7973240) specifically detects BCAR3 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7973240
发货至: 中国
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Quick Overview for BCAR3 抗体 (C-Term) (FITC) (ABIN7973240)

抗原

See all BCAR3 抗体
BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

适用

  • 26
  • 18
  • 15
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 2
  • 1

克隆类型

  • 27
  • 2
多克隆

标记

  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCAR3 antibody is conjugated to FITC

应用范围

  • 21
  • 13
  • 11
  • 7
  • 7
  • 5
  • 4
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-BCAR3 Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by five amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human BCAR3, different from the related mouse sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

    别名

    BCAR3

    背景

    Background: Breast cancer anti-estrogen resistance protein 3 is a protein that in humans is encoded by the BCAR3 gene. Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: BCAR3 adaptor protein, NSP family member

    基因ID

    8412

    UniProt

    O75815
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