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BACE1 抗体 (AA 185-432) (PE)

The PE-conjugated 兔 多克隆 anti-BACE1 antibody (ABIN7972649) specifically detects BACE1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7972649
发货至: 中国
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Quick Overview for BACE1 抗体 (AA 185-432) (PE) (ABIN7972649)

抗原

See all BACE1 抗体
BACE1 (Beta-secretase 1 (BACE1))

适用

  • 110
  • 75
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人, 小鼠, 大鼠

宿主

  • 99
  • 13
  • 2
  • 1
  • 1

克隆类型

  • 84
  • 32
多克隆

标记

  • 67
  • 6
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  • 1
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This BACE1 antibody is conjugated to PE

应用范围

  • 84
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  • 3
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  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 16
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    • 11
    • 7
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-432

    原理

    Anti-BACE1 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BACE1 recombinant protein (Position: A185-E432).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BACE1 (Beta-secretase 1 (BACE1))

    别名

    BACE1

    背景

    Background: Beta-secretase 1, also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1 (BACE1), membrane-associated aspartic protease 2, memapsin-2, aspartyl protease 2, and ASP2, is an enzyme that in humans is encoded by the BACE1 gene. This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.

    Gene Full Name: beta-secretase 1

    基因ID

    23621

    UniProt

    P56817
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