Beclin 1 抗体 (AA 1-354) (Fluoro594)
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北京 101111
Quick Overview for Beclin 1 抗体 (AA 1-354) (Fluoro594) (ABIN7972568)
抗原
See all Beclin 1 (BECN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-354
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原理
- Anti-Beclin 1/BECN1 Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Beclin 1 shares 97% amino acid (aa) sequence identity with both mouse,rat Beclin 1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Beclin 1 recombinant protein (Position: M1-S354). Human Beclin 1 shares 97% amino acid (aa) sequence identity with both mouse and rat Beclin 1.
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亚型
- IgG
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anti-Beclin 1, Autophagy Related (BECN1) (AA 201-330) antibody
BECN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB7463 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 2D12A3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IF, FACS, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-273) antibodyBECN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (C-Term) antibodyBECN1 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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别名
- BECN1
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背景
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Background: Beclin-1, also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. This gene participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Schizophrenia is associated with low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagywhich in turn results in increased neuronal cell death. It has been found that beclin-1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30, and in human MCF7 breast carcinoma cells.
Gene Full Name: beclin 1
Sequence Similarities: Belongs to the lipoxygenase family.
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基因ID
- 8678
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UniProt
- Q14457
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途径
- Autophagy
抗原
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