Beclin 1 抗体 (Middle Region) (Biotin)
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Quick Overview for Beclin 1 抗体 (Middle Region) (Biotin) (ABIN7972553)
抗原
See all Beclin 1 (BECN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Beclin 1/BECN1 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Beclin 1, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Beclin 1, Autophagy Related (BECN1) (AA 201-330) antibody
BECN1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB7463 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 2D12A3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IF, FACS, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-273) antibodyBECN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (C-Term) antibodyBECN1 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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别名
- BECN1
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背景
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Background: Bellini-1 (beclin 1, autophagy related) is a protein that in humans is encoded by the BECN1 gene, also known as BECN1, ATG6, VPS30, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. Human beclin encodes a novel 450-amino acid protein containing a coiled-coil region, within which it has limited homology to myosin-like proteins. Northern blot analysis of mouse and adult human tissues revealed widespread beclin expression. A 2.2-kb transcript was present at highest levels in human skeletal muscle and at detectable levels in all tissues examined. In some tissues, additional 1.7- and 1.4-kb transcripts were observed, suggesting the presence of alternatively spliced transcripts. Immunoperoxidase staining of human hippocampus and frontal cortex sections revealed beclin immunoreactivity in many neurons throughout these regions, as well as in some glial cells. Beclin protects against infection by a neurovirulent strain of Sindbis virus that is known to overcome the protective effects of Bcl2. Liang et al. showed that beclin reduced Sindbis virus replication in mouse brain and reduced Sindbis virus-induced cell death in mouse brain.
Gene Full Name: beclin 1
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基因ID
- 8678
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UniProt
- Q14457
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途径
- Autophagy
抗原
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