Aurora Kinase B 抗体 (N-Term) (Fluoro594)
Our Local Distributor
北京 101111
Quick Overview for Aurora Kinase B 抗体 (N-Term) (Fluoro594) (ABIN7971574)
抗原
See all Aurora Kinase B (AURKB) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- Anti-Aurora B/AURKB Antibody Fluoro594 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse Aurora B, different from the related rat sequence by two anino acids.
-
亚型
- IgG
-
-
anti-Aurora Kinase B (AURKB) (AA 1-90) antibody
AURKB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 6H7 unconjugated
anti-Aurora Kinase B (AURKB) (Internal Region) antibodyAURKB 适用: 人, 猴 IHC, WB, ELISA, FM 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 6-35) antibodyAURKB 适用: 人, 小鼠, 大鼠, 灵长类 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 1-90) antibodyAURKB 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6G8 unconjugated
anti-Aurora Kinase B (AURKB) (pThr232) antibodyAURKB 适用: 人, 小鼠, 大鼠, 猴 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase B (AURKB) (AA 89-251) antibodyAURKB 适用: 人 IHC 宿主: 小鼠 Monoclonal rAURKB-1592 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) antibodyAURKB 适用: 人 IHC, WB, ELISA, IP 宿主: 兔 Monoclonal 4E5 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) antibodyKD Validated AURKB 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB2295 unconjugated Recombinant Antibody
anti-Aurora Kinase B (AURKB) (AA 89-251) antibodyAURKB 适用: 人 IHC 宿主: 小鼠 Monoclonal AURKB-1592 unconjugated
anti-Aurora Kinase B (AURKB) (AA 1-255) antibodyAURKB 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- Aurora Kinase B (AURKB)
-
别名
- AURKB
-
背景
-
Background: AURKB (aurora kinase B) also called Aik2, AIM-1, ARK2, AurB, STK12, IPL1, PPP1R48 or STK5, localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. Cell cycle and Northern blot analyses showed that STK12 is expressed in the S phase and persistently thereafter. Western blot analysis indicated that STK12 is localized in the midbodies during anaphase. Northern blot analysis detected strong expression of a 1.5-kb STK12 transcript in thymus, with weaker expression in small intestine, testis, colon, spleen, and brain. The AURKB gene is mapped on 17p13.1. Examination of the role of both kinases in the phosphorylation of CENPA revealed that the reaction is mediated sequentially by AURKA and AURKB in early mitosis. EB1 overexpression enhanced AURKB kinase activity, and knockdown of EB1 with small interfering RNA impaired AURKB activity. EB1 protected AURKB from dephosphorylation/inactivation by protein phosphatase-2A by blocking binding of PP2A to AURKB.
Gene Full Name: aurora kinase B
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
-
基因ID
- 20877
-
UniProt
- O70126
-
途径
- TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
抗原
-
