ARID1A 抗体 (AA 857-1552) (Fluoro550)
Our Local Distributor
北京 101111
Quick Overview for ARID1A 抗体 (AA 857-1552) (Fluoro550) (ABIN7970450)
抗原
See all ARID1A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 857-1552
-
原理
- Anti-ARID1A Antibody Fluoro550 Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human ARID1A recombinant protein (Position: R857-Q1552).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
-
别名
- ARID1A
-
背景
-
Background: AT-rich interactive domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene. This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: AT-rich interaction domain 1A
-
基因ID
- 8289
-
UniProt
- O14497
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
抗原
-