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ARID1A 抗体

The 兔 单克隆 anti-ARID1A antibody is suitable to detect ARID1A in samples from 人. It has been validated for WB, IHC 和 IF.
产品编号 ABIN7265699
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ARID1A 抗体 (ABIN7265699)

抗原

See all ARID1A 抗体
ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

适用

  • 50
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  • 1
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宿主

  • 47
  • 3

克隆类型

  • 27
  • 23
单克隆

标记

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  • 3
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  • 3
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  • 1
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  • 1
This ARID1A antibody is un-conjugated

应用范围

  • 27
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  • 8
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    ARID1A Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human ARID1A

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

    别名

    ARID1A

    背景

    This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],B120, BAF250, BAF250a, BM029, C1orf4, CSS2, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1,Cancer,Chromatin Remodeling,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear Receptor Signaling_Nuclear hormone receptors,Signal Transduction,ARID1A

    分子量

    kDa

    基因ID

    8289

    UniProt

    O14497

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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