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ARID1A 抗体 (AA 1800-2000)

The 小鼠 单克隆 anti-ARID1A antibody is suitable to detect ARID1A in samples from 人. It has been validated for IHC.
产品编号 ABIN7859298
发货至: 中国
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Quick Overview for ARID1A 抗体 (AA 1800-2000) (ABIN7859298)

抗原

See all ARID1A 抗体
ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ARID1A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

ARID1A-7736
  • 抗原表位

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    AA 1800-2000

    原理

    ARID1A / SMARCF1 Antibody

    特异性

    The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1800-2000) of human ARID1A protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

    别名

    ARID1A

    背景

    actin-dependent regulator of chromatin subfamily F member 1, ARID domain containing protein 1A, AT rich interactive domain 1A (SWI like), AT rich interactive domain containing protein 1A, B120, BAF250, BAF250A, BM029, brain protein 120, BRG1-associated factor 250a, C1ORF4, chromatin remodeling factor p250, chromosome 1 open reading frame 4, ELD, hELD, hOSA1, matrix-associated, MRD14, OSA1 nuclear protein, P270, SMARCF1, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1

    Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL, and at a much lower level in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

    分子量

    165-320kDa

    基因ID

    8289, 468972

    UniProt

    O14497

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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