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ARNT 抗体 (AA 416-789)

This 兔 多克隆 antibody specifically detects ARNT in WB. It exhibits reactivity toward 人.
产品编号 ABIN7970268
发货至: 中国
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Quick Overview for ARNT 抗体 (AA 416-789) (ABIN7970268)

抗原

See all ARNT 抗体
ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

适用

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宿主

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克隆类型

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多克隆

标记

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This ARNT antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

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    AA 416-789

    原理

    Anti-HIF1 beta/ARNT Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human HIF1 beta shares 86%,83% amino acid (aa) sequences identity with mouse,rat HIF1 beta,respectively.

    产品特性

    Anti-HIF1 beta/ARNT Antibody. Tested in WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HIF1 beta recombinant protein (Position: V416-E789). Human HIF1 beta shares 86% and 83% amino acid (aa) sequences identity with mouse and rat HIF1 beta, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

    别名

    ARNT

    背景

    Background: ARNT is also known as HIF1-beta or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. ARNT is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism.

    Gene Full Name: aryl hydrocarbon receptor nuclear translocator

    Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

    分子量

    87 kDa

    基因ID

    405

    UniProt

    P27540

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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