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Recombinant ARNT 抗体

ARNT 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Monoclonal 2F11 unconjugated Recombinant Antibody
产品编号 ABIN7127344
发货至: 中国
  • 抗原 See all ARNT 抗体
    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
    抗体类型
    Recombinant Antibody
    适用
    • 54
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    宿主
    • 42
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    克隆类型
    • 38
    • 19
    单克隆
    标记
    • 43
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    This ARNT antibody is un-conjugated
    应用范围
    • 39
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human ARNT
    克隆位点
    2F11
    亚型
    IgG
    Top Product
    Discover our top product ARNT Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
    别名
    ARNT (ARNT 产品)
    别名
    HIF-1-beta antibody, HIF-1beta antibody, HIF1-beta antibody, HIF1B antibody, HIF1BETA antibody, TANGO antibody, bHLHe2 antibody, D3Ertd557e antibody, Drnt antibody, ESTM42 antibody, Hif1b antibody, W08714 antibody, mKIAA4051 antibody, Arnt1 antibody, ARNT antibody, zgc:136664 antibody, arnt1 antibody, hif1b antibody, tango antibody, xArnt antibody, hif1beta antibody, hif-1beta antibody, arnt.2 antibody, MGC68805 antibody, aryl hydrocarbon receptor nuclear translocator antibody, aryl hydrocarbon receptor nuclear translocator S homeolog antibody, ARNT antibody, Arnt antibody, arnt antibody, arnt.S antibody
    背景

    Background: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).

    Aliases: Aryl hydrocarbon receptor nuclear translocator, ARNT protein, Class E basic helix-loop-helix protein 2, bHLHe2, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, HIF-1-beta, HIF1-beta, ARNT, BHLHE2

    UniProt
    P27540
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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