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ARNT 抗体 (AA 416-789) (FITC)

The 兔 多克隆 anti-ARNT antibody is suitable to detect ARNT in samples from 人. It has been validated for FACS.
产品编号 ABIN7970263
发货至: 中国
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Quick Overview for ARNT 抗体 (AA 416-789) (FITC) (ABIN7970263)

抗原

See all ARNT 抗体
ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

适用

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宿主

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克隆类型

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多克隆

标记

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This ARNT antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 416-789

    原理

    Anti-HIF1 beta/ARNT Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human HIF1 beta shares 86%,83% amino acid (aa) sequences identity with mouse,rat HIF1 beta,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HIF1 beta recombinant protein (Position: V416-E789). Human HIF1 beta shares 86% and 83% amino acid (aa) sequences identity with mouse and rat HIF1 beta, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

    别名

    ARNT

    背景

    Background: ARNT is also known as HIF1-beta or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. ARNT is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism.

    Gene Full Name: aryl hydrocarbon receptor nuclear translocator

    Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

    基因ID

    405

    UniProt

    P27540

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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