ALOX5 抗体 (C-Term) (Fluoro594)
Our Local Distributor
北京 101111
Quick Overview for ALOX5 抗体 (C-Term) (Fluoro594) (ABIN7969855)
抗原
See all ALOX5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Anti-5 Lipoxygenase/ALOX5 Antibody Fluoro594 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- different from the related rat,mouse sequences by two amino acids.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX5, different from the related rat and mouse sequences by two amino acids.
-
亚型
- IgG
-
-
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 461-671) antibody
ALOX5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 1-674) antibodyALOX5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 1-300) antibodyALOX5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) antibodyALOX5 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 601-674) antibodyALOX5 适用: 人, 小鼠, 大鼠 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 120-483) antibodyALOX5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (C-Term) antibodyALOX5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 461-671) antibodyALOX5 适用: 人 WB 宿主: 小鼠 Monoclonal D10 unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 2-149) antibodyALOX5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) antibodyALOX5 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 1D4 unconjugated Recombinant Antibody
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
-
别名
- ALOX5
-
背景
-
Background: ALOX5 (ARACHIDONATE 5-LIPOXYGENASE), also known as LOG5 or 5-LO (5-LIPOXYGENASE), is an enzyme that in humans is encoded by the ALOX5 gene. ALOX5 is a member of the lipoxygenase family of enzymes which also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. The enzyme 5-lipoxygenase catalyzes 2 reactions in the formation of leukotrienes. The ALOX5 gene is mapped to chromosome 10q11.21 based on an alignment of the ALOX5 sequence with the genomic sequence. Human 5-LO contains 3 nuclear localization sequences (NLSs) and a phosphorylation site involved in nuclear localization. Compared with age-matched 5-LO competent mice, the 5-LO knockout mice developed less right heart hypertrophy. Pharmacologic inhibition or ALOX5 gene disruption resulted in a significant decrease of beta-amyloid production and gamma-secretase levels. ALOX5 activity is short-lived, apparently in part because of an intrinsic instability of the enzyme.
Gene Full Name: arachidonate 5-lipoxygenase
Sequence Similarities: Belongs to the lipoxygenase family.
-
基因ID
- 240
-
UniProt
- P09917
抗原
-
