我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Mre11 抗体 (AA 451-550)

Name: Mre11 抗体 (AA 451-550)
SKU: ABIN747293
Availability: OutOfStock

This anti-Mre11 antibody is a 兔多克隆 antibody detecting Mre11 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Mre11/HNGS1 Polyclonal Antibody, Unconjugated (ABIN747293) at 1:200, followed by conjugation to the secondary antibody and DAB staining (Mre11 抗体 (AA 451-550))

IHC

L1 rat liver lysates L2 rat brain lysates probed with Anti Mre11/HNGS1 Polyclonal Antibody, Unconjugated (ABIN747293) at 1:200 overnight at 4 °C. (Mre11 抗体 (AA 451-550))

SDS

2 images

(1 reference)

产品编号 ABIN747293

发货至: 中国

Quick Overview for Mre11 抗体 (AA 451-550) (ABIN747293)

抗原

See all Mre11 (MRE11A) 抗体

Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This Mre11 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product MRE11A Primary Antibody

抗原表位
21

14

7

5

4

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 451-550

交叉反应

大鼠

预测反应

Human,Mouse,Dog,Cow,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Mre11/HNGS1

亚型

IgG
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibody
MRE11A 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) antibody
MRE11A 适用: 人, 大鼠, 小鼠, 小鸡, Hamster WB, IHC, IP, IF, ICC, FACS, ChIP 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibody
MRE11A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 375-609) antibody
MRE11A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibody
MRE11A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (C-Term) antibody
MRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Internal Region) antibody
MRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 2-239) antibody
MRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-206) antibody
MRE11A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H4-F4 unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Ser916) antibody
MRE11A 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).
抗原

Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

别名

Mre11

背景

Synonyms: ATLD, HNGS1, MRE11, MRE11B, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A, MRE11A
Background: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation.

基因ID

4361

UniProt

P49959

途径

DNA Damage Repair