APOB 抗体 (AA 246-450)
Our Local Distributor
北京 101111
Quick Overview for APOB 抗体 (AA 246-450) (ABIN7969355)
抗原
See all APOB 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 246-450
-
原理
- Anti-Apolipoprotein B/APOB Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450). Human Apolipoprotein B shares 82.4%,80.5% amino acid (aa) sequence identity with mouse,rat Apolipoprotein B,respectively.
-
产品特性
- Anti-Apolipoprotein B/APOB Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450). Human Apolipoprotein B shares 82.4% and 80.5% amino acid (aa) sequence identity with mouse and rat Apolipoprotein B, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Western blot, 0.1-0.5 μg/mL, Human
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- APOB (Apolipoprotein B (APOB))
-
别名
- APOB
-
背景
-
Background: Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Gene Full Name: apolipoprotein B
-
分子量
- 250 kDa
-
基因ID
- 338
-
UniProt
- P04114
-
途径
- Lipid Metabolism
抗原
-