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APOA1 抗体 (AA 25-264) (Fluoro488)

This 小鼠 单克隆 antibody specifically detects APOA1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7969314
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for APOA1 抗体 (AA 25-264) (Fluoro488) (ABIN7969314)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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宿主

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小鼠

克隆类型

  • 152
  • 82
单克隆

标记

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This APOA1 antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)

克隆位点

17G5
  • 抗原表位

    • 26
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    AA 25-264

    原理

    Anti-Apolipoprotein A I APOA1 Antibody (monoclonal, 17G5) Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    coli-derived mouse Apolipoprotein A I recombinant protein (Position: D25-Q264). Mouse Apolipoprotein A I shares 64%,68.6% amino acid (aa) sequence identity with human,rat Apolipoprotein A I,respectively.

    纯化方法

    Affinity-chromatography

    免疫原

    E. coli-derived mouse Apolipoprotein A I recombinant protein (Position: D25-Q264). Mouse Apolipoprotein A I shares 64% and 68.6% amino acid (aa) sequence identity with human and rat Apolipoprotein A I, respectively.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    APOA1

    背景

    Background: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.

    Gene Full Name: apolipoprotein A1

    基因ID

    335

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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