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APOA1 抗体 (AA 25-259)

The 兔 多克隆 anti-APOA1 antibody is suitable to detect APOA1 in samples from 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN7969300
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APOA1 抗体 (AA 25-259) (ABIN7969300)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This APOA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

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    AA 25-259

    原理

    Anti-Apolipoprotein A I/APOA1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    coli-derived rat APOA1 recombinant protein (Position: D25-A259). Rat APOA1 shares 61.7%,68.6% amino acid (aa) sequence identity with human,mouse APOA1,respectively.

    产品特性

    Anti-Apolipoprotein A I/APOA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived rat APOA1 recombinant protein (Position: D25-A259). Rat APOA1 shares 61.7% and 68.6% amino acid (aa) sequence identity with human and mouse APOA1, respectively.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat Western blot, 0.1-0.5 μg/mL, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    Apoa1

    背景

    Background: Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.

    Gene Full Name: apolipoprotein A1

    分子量

    24 kDa

    基因ID

    25081

    UniProt

    P04639

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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