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APC2 抗体 (N-Term) (Biotin)

This 兔 多克隆 antibody specifically detects APC2 in ELISA, WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7969224
发货至: 中国
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Quick Overview for APC2 抗体 (N-Term) (Biotin) (ABIN7969224)

抗原

See all APC2 抗体
APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

适用

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宿主

  • 38
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克隆类型

  • 38
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多克隆

标记

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This APC2 antibody is conjugated to Biotin

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    Anti-APC2 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human APC2, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))

    别名

    APC2

    背景

    Background: APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

    Gene Full Name: APC regulator of Wnt signaling pathway 2

    基因ID

    10297

    UniProt

    O95996

    途径

    WNT signaling
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