ANGPTL4 抗体 (AA 39-406) (APC)
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Quick Overview for ANGPTL4 抗体 (AA 39-406) (APC) (ABIN7968604)
抗原
See all ANGPTL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-406
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原理
- Anti-ANGPTL4 Antibody APC Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human ANGPTL4 shares 75.6%,76.6% amino acid (aa) sequence identity with mouse,rat ANGPTL4,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ANGPTL4 recombinant protein (Position: D39-S406). Human ANGPTL4 shares 75.6% and 76.6% amino acid (aa) sequence identity with mouse and rat ANGPTL4, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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别名
- ANGPTL4
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背景
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Background: Angiopoietin-like 4 is a protein that in humans is encoded by the ANGPTL4 gene.[5][6][7] Alternatively spliced transcript variants encoded with different isoforms have been described. This gene was previously referred to as ANGPTL2, HFARP, PGAR, or FIAF but has been renamed ANGPTL4. This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
Gene Full Name: angiopoietin like 4
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基因ID
- 51129
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UniProt
- Q9BY76
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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