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Angiopoietin 2 抗体 (C-Term) (HRP)

This 兔 多克隆 antibody specifically detects Angiopoietin 2 in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7968526
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Angiopoietin 2 抗体 (C-Term) (HRP) (ABIN7968526)

抗原

See all Angiopoietin 2 (ANGPT2) 抗体
Angiopoietin 2 (ANGPT2)

适用

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宿主

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克隆类型

  • 114
  • 48
多克隆

标记

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This Angiopoietin 2 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    C-Term

    原理

    Anti-Angiopoietin 2/ANGPT2 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Angiopoietin 2.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Angiopoietin 2 (ANGPT2)

    别名

    ANGPT2

    背景

    Background: Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.

    Gene Full Name: angiopoietin 2

    Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

    基因ID

    285

    UniProt

    O15123

    途径

    RTK signaling
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