Amphiregulin 抗体 (AA 101-180)
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北京 101111
Quick Overview for Amphiregulin 抗体 (AA 101-180) (ABIN7968156)
抗原
See all Amphiregulin (AREG) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 101-180
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原理
- Anti-Amphiregulin/AREG Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Amphiregulin/AREG Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Amphiregulin/AREG recombinant protein (Position: S101-R180).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- Amphiregulin (AREG)
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别名
- AREG
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背景
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Background: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.
Gene Full Name: amphiregulin
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分子量
- 45 kDa
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基因ID
- 374
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UniProt
- P15514
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途径
- RTK signaling, EGFR Signaling Pathway
抗原
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