AKR1C2 抗体 (AA 1-123) (HRP)
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北京 101111
Quick Overview for AKR1C2 抗体 (AA 1-123) (HRP) (ABIN7967613)
抗原
See all AKR1C2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-123
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原理
- Anti-AKR1C1/C2 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human AKR1C1/C2 recombinant protein (Position: M1-K123).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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别名
- AKR1C2
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背景
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Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Gene Full Name: aldo-keto reductase family 1 member C2
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基因ID
- 1645, 1646
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UniProt
- P52895
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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