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AKR1C2 抗体

The 小鼠 单克隆 anti-AKR1C2 antibody is suitable to detect AKR1C2 in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN6939232
发货至: 中国
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Quick Overview for AKR1C2 抗体 (ABIN6939232)

抗原

See all AKR1C2 抗体
AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This AKR1C2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

CPTC-AKR1C2-1
  • 原理

    Aldo-keto Reductase Family 1 Member C2 / DD2 Antibody

    特异性

    DDH2 / AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human full-length AKR1C2 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Positive Control: HeLa, K-562, A431, HepG2, A549 cells. Human liver or stomach tissue.

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

    别名

    AKR1C2

    背景

    AKR1C2, 3-alpha-HSD3, AKR1C-pseudo protein, BABP, Dihydrodiol dehydrogenase 2, DD-2, MCDR2, HAKRD, DD, DDH2, HBAB, Pseudo-chlordecone reductase, SRXY8

    A431, A549 cells. Human liver or stomach tissue., HeLa, Hep G2, K-562

    分子量

    37kDa

    基因ID

    1646, 567256

    UniProt

    P52895

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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