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CDK2 抗体 (pThr160)

CDK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN747008
发货至: 中国
  • 抗原 See all CDK2 抗体
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    抗原表位
    • 29
    • 28
    • 17
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    • 15
    • 10
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    • 5
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    • 1
    • 1
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    • 1
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    pThr160
    适用
    • 175
    • 96
    • 76
    • 10
    • 10
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
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    • 2
    人, 小鼠, 大鼠
    宿主
    • 182
    • 17
    • 1
    克隆类型
    • 171
    • 29
    多克隆
    标记
    • 94
    • 19
    • 15
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    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
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    This CDK2 antibody is un-conjugated
    应用范围
    • 168
    • 75
    • 51
    • 50
    • 48
    • 39
    • 29
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    • 18
    • 12
    • 10
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human CDK2 around the phosphorylation site of Thr160 [TY(p-T)HE]
    亚型
    IgG
    Top Product
    Discover our top product CDK2 Primary Antibody
  • 应用备注
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • Mlcochova, Sutherland, Watters, Bertoli, de Bruin, Rehwinkel, Neil, Lenzi, Kim, Khwaja, Gage, Georgiou, Chittka, Yona, Noursadeghi, Towers, Gupta: "A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages." in: The EMBO journal, Vol. 36, Issue 5, pp. 604-616, (2017) (PubMed).

  • 抗原
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    别名
    Cdk2 (CDK2 产品)
    别名
    p33(CDK2) antibody, A630093N05Rik antibody, wu:fa10c02 antibody, zgc:56598 antibody, zgc:77684 antibody, eg1 antibody, CDKN2 antibody, cdk2L antibody, cyclin dependent kinase 2 antibody, cyclin-dependent kinase 2 antibody, cyclin-dependent kinase 2 S homeolog antibody, CDK2 antibody, Cdk2 antibody, cdk2 antibody, cdk2.S antibody
    背景

    Synonyms: p-CDH2 Thr160, CDH2 Thr160, CDH2 T160,Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2_HUMAN.

    Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

    基因ID
    1017
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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