Adenylate Kinase 2 抗体 (AA 161-239) (Fluoro550)
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Quick Overview for Adenylate Kinase 2 抗体 (AA 161-239) (Fluoro550) (ABIN7966807)
抗原
See all Adenylate Kinase 2 (AK2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-239
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原理
- Anti-AK2 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- coli-derived human AK2 recombinant protein (Position: E161-I239). Human AK2 shares 93.7%,93% amino acid (aa) sequence identity with mouse,rat AK2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human AK2 recombinant protein (Position: E161-I239). Human AK2 shares 93.7% and 93% amino acid (aa) sequence identity with mouse and rat AK2, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Adenylate Kinase 2 (AK2)
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别名
- AK2
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背景
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Background: Adenylate kinase 2 is an enzyme is encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space of the mitochondrion. Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates, this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Gene Full Name: adenylate kinase 2
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基因ID
- 204
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UniProt
- P54819
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途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
抗原
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