alpha Actinin 4 抗体 (AA 561-661)
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北京 101111
Quick Overview for alpha Actinin 4 抗体 (AA 561-661) (ABIN7965747)
抗原
See all alpha Actinin 4 (ACTN4) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 561-661
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原理
- Anti-Alpha Actinin 4/ACTN4 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Alpha Actinin 4 shares 99%,98% amino acid (aa) sequence identity with mouse,rat Alpha Actinin 4,respectively.
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产品特性
- Anti-Alpha Actinin 4/ACTN4 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Alpha Actinin 4 recombinant protein (Position: E561-V661). Human Alpha Actinin 4 shares 99% and 98% amino acid (aa) sequence identity with mouse and rat Alpha Actinin 4, respectively.
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亚型
- IgG
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anti-Actinin, alpha 4 (ACTN4) (AA 592-701) antibody
ACTN4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 1-269) antibodyACTN4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (C-Term) antibodyACTN4 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyACTN4 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibodyACTN4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 785-813), (C-Term) antibodyACTN4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15705 unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 160-440) antibodyACTN4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyACTN4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 1-911) antibodyACTN4 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyKO Validated ACTN4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB535 unconjugated Recombinant Antibody
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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别名
- ACTN4
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背景
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Background: Alpha-actinin-4 is a protein that in humans is encoded by the ACTN4 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This ACTN4 gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Gene Full Name: actinin alpha 4
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分子量
- 105 kDa
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基因ID
- 81
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UniProt
- O43707
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途径
- Proton Transport
抗原
-
