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alpha Actinin 4 抗体 (AA 561-661) (PE)

This 兔 多克隆 antibody specifically detects alpha Actinin 4 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7965745
发货至: 中国
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Quick Overview for alpha Actinin 4 抗体 (AA 561-661) (PE) (ABIN7965745)

抗原

See all alpha Actinin 4 (ACTN4) 抗体
alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

适用

  • 143
  • 83
  • 78
  • 8
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 123
  • 20

克隆类型

  • 87
  • 55
多克隆

标记

  • 72
  • 10
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
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  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This alpha Actinin 4 antibody is conjugated to PE

应用范围

  • 101
  • 50
  • 38
  • 36
  • 31
  • 28
  • 21
  • 16
  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
    • 10
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 561-661

    原理

    Anti-Alpha Actinin 4/ACTN4 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Alpha Actinin 4 shares 99%,98% amino acid (aa) sequence identity with mouse,rat Alpha Actinin 4,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Alpha Actinin 4 recombinant protein (Position: E561-V661). Human Alpha Actinin 4 shares 99% and 98% amino acid (aa) sequence identity with mouse and rat Alpha Actinin 4, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

    别名

    ACTN4

    背景

    Background: Alpha-actinin-4 is a protein that in humans is encoded by the ACTN4 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This ACTN4 gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.

    Gene Full Name: actinin alpha 4

    基因ID

    81

    UniProt

    O43707

    途径

    Proton Transport
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