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ABI1 抗体 (C-Term) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-ABI1 antibody (ABIN7965342) specifically detects ABI1 in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7965342
发货至: 中国
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Quick Overview for ABI1 抗体 (C-Term) (Cy3) (ABIN7965342)

抗原

See all ABI1 抗体
ABI1 (Abl-Interactor 1 (ABI1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ABI1 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-SSH3BP1/ABI1 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related rat,mouse sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ABI1, different from the related rat and mouse sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ABI1 (Abl-Interactor 1 (ABI1))

    别名

    ABI1

    背景

    Background: ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

    Gene Full Name: abl interactor 1

    Sequence Similarities: Contains 12 fibronectin type-I domains.

    基因ID

    10006

    UniProt

    Q8IZP0

    途径

    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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