HTR2C 抗体 (AA 372-458) (HRP)
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北京 101111
Quick Overview for HTR2C 抗体 (AA 372-458) (HRP) (ABIN7965083)
抗原
See all HTR2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 372-458
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原理
- Anti-5-HT2C Receptor/HTR2C Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human 5-HT2C Receptor/HTR2C recombinant protein (Position: N372-V458).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
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别名
- HTR2C
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背景
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Background: This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.
Gene Full Name: 5-hydroxytryptamine receptor 2C
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基因ID
- 3358
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UniProt
- P28335
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
抗原
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