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Recombinant HTR2C 抗体

HTR2C 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 9H8 unconjugated Recombinant Antibody
产品编号 ABIN7127314
发货至: 中国
  • 抗原 See all HTR2C 抗体
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    抗体类型
    Recombinant Antibody
    适用
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    克隆类型
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    单克隆
    标记
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    This HTR2C antibody is un-conjugated
    应用范围
    • 59
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human 5HT2C Receptor
    克隆位点
    9H8
    亚型
    IgG
    Top Product
    Discover our top product HTR2C Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    别名
    HTR2C (HTR2C 产品)
    别名
    5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-HT2cR antibody, 5HT1c antibody, Htr1c antibody, SR1 antibody, 5HT-1C antibody, 5HT2C antibody, 5-HT-2C antibody, 5-ht2cr antibody, si:dkey-24g18.2 antibody, 5ht2c antibody, 5HTR2C antibody, 5-hydroxytryptamine receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody, HTR2C antibody, Htr2c antibody, htr2c.S antibody, htr2cl1 antibody, LOC407134 antibody
    背景

    Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.

    Aliases: 5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C), HTR2C, HTR1C

    UniProt
    P28335
    途径
    Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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