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ABAT 抗体 (AA 388-500) (HRP)

This 兔 多克隆 antibody specifically detects ABAT in WB, IHC 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7965028
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ABAT 抗体 (AA 388-500) (HRP) (ABIN7965028)

抗原

See all ABAT 抗体
ABAT (4-Aminobutyrate Aminotransferase (ABAT))

适用

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人, 小鼠, 大鼠

宿主

  • 64
  • 5

克隆类型

  • 53
  • 16
多克隆

标记

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This ABAT antibody is conjugated to HRP

应用范围

  • 53
  • 25
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 11
    • 4
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    • 1
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    AA 388-500

    原理

    Anti-ABAT Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    coli-derived human ABAT recombinant protein (Position: K388-K500). Human ABAT shares 93.9%,94.5% amino acid (aa) sequence identity with mouse,rat ABAT,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human ABAT recombinant protein (Position: K388-K500). Human ABAT shares 93.9% and 94.5% amino acid (aa) sequence identity with mouse and rat ABAT, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    ABAT (4-Aminobutyrate Aminotransferase (ABAT))

    别名

    ABAT

    背景

    Background: 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. ABAT is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5- phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of humans ynapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractoryseizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

    Gene Full Name: 4-aminobutyrate aminotransferase

    Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

    基因ID

    18

    UniProt

    P80404

    途径

    Monocarboxylic Acid Catabolic Process
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