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ABAT 抗体 (C-Term)

ABAT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854328
发货至: 中国
  • 抗原 See all ABAT 抗体
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    抗原表位
    • 15
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 39
    • 26
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    宿主
    • 35
    • 5
    克隆类型
    • 34
    • 6
    多克隆
    标记
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ABAT antibody is un-conjugated
    应用范围
    • 39
    • 15
    • 13
    • 13
    • 9
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to ABAT (4-aminobutyrate aminotransferase)
    ABAT antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human ABAT. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ABAT Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse brain , Rat liver

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.49 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    别名
    4-aminobutyrate aminotransferase (ABAT 产品)
    别名
    cb880 antibody, fj82a01 antibody, wu:fj82a01 antibody, BA0325 antibody, PSPTO0259 antibody, PSPTO0301 antibody, PSPTO1890 antibody, GABA-AT antibody, GABAT antibody, NPD009 antibody, GABA-T antibody, L-AIBAT antibody, 9630038C02Rik antibody, AI255750 antibody, ENSMUSG00000051226 antibody, Gabaat antibody, Gabat antibody, Gm9851 antibody, I54 antibody, Laibat antibody, X61497 antibody, beta-AlaAT antibody, 4-aminobutyrate aminotransferase antibody, 4-aminobutyrate--2-oxoglutarate transaminase antibody, GABA aminotransferase PLP-dependent PuuE antibody, 4-aminobutyrate aminotransferase, mitochondrial antibody, aspartate aminotransferase family protein antibody, 4-aminobutyrate aminotransferase S homeolog antibody, ABAT antibody, abat antibody, gabT antibody, puuE antibody, gabT-1 antibody, gabT-2 antibody, gabT-3 antibody, CNE01830 antibody, Mmwyl1_0047 antibody, CpipJ_CPIJ008729 antibody, KCR_RS04555 antibody, Bcenmc03_4909 antibody, Hden_0972 antibody, Dbac_2000 antibody, Mesil_2400 antibody, Trad_0121 antibody, abat.S antibody, Abat antibody
    背景
    4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

    Cellular Localization: Mitochondrion matrix
    分子量
    56 kDa
    基因ID
    18
    UniProt
    P80404
    途径
    Monocarboxylic Acid Catabolic Process
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