Recombinant UBE2S 抗体
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北京 101111
Quick Overview for Recombinant UBE2S 抗体 (ABIN7938534)
抗原
See all UBE2S 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- UBE2S antibody (rAb), 100 μg (Clone 6D18)
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纯化方法
- Protein A Chromatography
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免疫原
- This antibody was raised against the UBE2S fusion protein.
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) antibody
UBE2S 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1B5 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 122-221) antibodyUBE2S 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 1-209) antibodyUBE2S 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (N-Term) antibodyVerified UBE2S 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) antibodyUBE2S 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 4G2 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 183-210), (C-Term) antibodyUBE2S 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB42367 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 10-40), (N-Term) antibodyUBE2S 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4163 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 1-222) antibodyUBE2S 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 1-222) antibodyUBE2S 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2S (UBE2S) (AA 1-222) antibodyUBE2S 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal AT2C12 unconjugated
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应用备注
- WB: 1:5000-1:50000 dilution IHC: 1:2000-1:10000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))
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别名
- UBE2S
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背景
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Background_Plain: UBE2S (Ubiquitin-conjugating enzyme E2 S) also known as E2-EPF, E2EPF and EPF5. UBE2S is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. UBE2S can accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro, it is however unclear whether UBE2D1/UBCH5 acts as an E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination.
Aliases: Ubiquitin conjugating enzyme E2 S, E2-EPF, E2EPF, EPF5
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分子量
- 24 kDa
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途径
- Ubiquitin Proteasome Pathway
抗原
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